Anemia symptoms and causes

Anemia definition

Anemia literally means lack of blood. In medical terms, anemia specifically means lack of oxygen carrying red component of your blood. The actual substance that carries oxygen in your blood is hemoglobin. This hemoglobin is contained inside the red blood cells. Therefore, anemia means a lack of hemoglobin or lack of red blood cells.

Anemia symptoms

Are you looking pale and feeling tired? If yes, you need to think about anemia symptoms.

There are many signs of anemia in adults. Lack of hemoglobin affects many different organ systems in your body. We will look at anemia symptoms based on the organ affected by anemia.

Anemia symptoms that affect your whole body

Some anemia symptoms affect your whole body. When you have insufficient hemoglobin in your blood, you have less oxygen circulating in your blood. Due to insufficient oxygen, your whole body suffers.

Here are some of the anemia symptoms that affect your whole body

  1. Feeling tired all the time: Anemia makes you feel tired all the time. You may feel like you have no energy at all. You may be asking yourself, “Why am so tired all the time?”
  2. Extreme fatigue: As your anemia worsens, your symptoms progress from feeling tired all the time to extreme fatigue. You struggle with your daily routine. You get exhausted after minimal activity.
  3. Malaise: As anemia symptoms worsen, you not only have fatigue but also start to have malaise. You do not feel well. You are uncomfortable and restless. Your whole body struggles to find a sense of well being.
  4. Dizziness when standing up: Dizziness and lightheadedness when standing up results from a shift in your blood circulation when you stand up. Even under normal condition, more blood flows to your legs when you go from sitting position to standing. This leads to less blood being available to your brain. When you have anemia, your blood is already carrying less oxygen than normal. When you divert some of this anemic blood away from your brain, your brain does not get enough oxygen and you feel lightheaded and dizzy.
  5. Muscle weakness: In addition to feeling tired, fatigued and having low energy, anemia may actually make you feel like you have muscle weakness. This muscle weakness associated with anemia is a form of generalized muscle weakness. It means that all your muscles are weak, not just a group of specific muscles.

Anemia symptoms that affect your heart

  1. Heart palpitations: Heart palpitations symptoms are very common with anemia. People with anemia do not have enough oxygen circulating in their bodies. The heart tries to compensate for the lack of oxygen by pumping more blood. The heart beats faster and harder. People with anemia feel their hearts pounding in their chests. In some people, heart palpitations symptoms may sometimes be the only symptoms of being anemic.
  2. Chest pain: Chest pain from anemia does not usually happen in people with normal healthy hearts. However people with underlying coronary artery disease may have chest pain due to anemia. In those people, the lack of oxygen related to anemia acts as a “stress test” to unmask the symptoms of coronary artery narrowing.
  3. Shortness of breath with activity: People with anemia my feel like they are out of breath with little exertion.
  4. Anemia heart murmur: Heart mummer is one of the important signs of anemia that doctors can discover when examining people with anemia. Heart murmur in anemia may be present even without any structural abnormality of the heart. This type of heart murmur is sometimes called a functional heart mummer to distinguish it from other types of heart murmur that indicate leaky heart valves or other structural problems with one or more of the heart valves.
  5. Syncope and collapse (Fainting): People with anemia may experience fainting or passing out as the anemia worsens.

Anemia symptoms that affect your brain and the nervous system:

  1. Mental slowing and confusion: People with anemia may have some cognitive dysfunction related to low levels of oxygen in their brains. Mental slowing and confusion from anemia is usually the result of untreated anemia for a long time.
  2. Irritability: People with untreated anemia may become very irritable over time as lack of enough oxygen affects their brain function.
  3. Depression and mood swings: It is important to check for anemia in anyone being evaluated for depression and other mood disorders because people with anemia may develop these mental abnormalities from brain dysfunction related to lack of oxygen.
  4. Memory loss: In addition to general mental slowing and confusion, one specific type of anemia can cause disproportionate amount of memory loss. Memory loss from anemia is especially prominent in vitamin B12 deficiency anemia.

Signs of anemia in fingernails

  1. Spoon shaped nails: People with anemia may develop spoon shaped nails. Spoon shaped nails (medically known as Koilonychia) is especially prominent in people with long standing iron deficiency anemia.
  2. Brittle nails: In addition to spoon shaped nails, brittle nails are also important signs of possible iron deficiency anemia.

Signs of anemia in your skin

  1. Skin pallor: Pale skin is an important sign of anemia. There are two main reasons why people with anemia develop pale skin. First, lack of the red pigment hemoglobin makes the skin appear pale. Second, their bodies try to adapt to the lack of oxygen by decreasing the supply of blood to the skin. The blood vessels in the skin of people with anemia constrict to divert blood away from the skin. This allows other vital organs get more oxygen. Due to the decreased blood supply, the skin of people with anemia appears paler than they would from just the lack of hemoglobin.
  2. Pallor in dark skin: In people with darker skins, it is difficult to see pallor because of the high levels of skin pigment. However, normal dark skin has more of a warm tone to it. Anemic dark skin has a colder tone. Dark skin almost appears ashen when anemic.
  3. Jaundice: Jaundice or yellow discoloration of the skin happens in people with anemia of a very specific type. It is called hemolytic anemia or anemia related to the destruction of red blood cells.

Signs of anemia in your hair

picture iron deficiency hair loss

Hair loss and thinning of hair: Iron deficiency anemia is an important cause of hair loss and thinning of hair. In fact, iron deficiency even without anemia has been found to be an important cause of thinning hair in women.

Signs of anemia in the eyes: how to tell if you are anemic by your eyes?

picture anemia symptoms eyes: anemia eyelids images
anemia eyes vs normal eyes


It is possible to tell if you are anemic by examining your eyes in a certain way. You need to pull your lower eyelid down with your finger. Then you need to look closely at the inner everted part of your lower eyelid. You can then take a selfie or ask your partner to take a picture of your eye. As you can see in the picture, normal lower eyelid when everted looks vibrant red in color. If it looks pale like the one on the right side of the picture, then you can almost certainly tell that you are anemic.

Anemia diagnosis: How to test for anemia?

It is easy to make the diagnosis of anemia. All you need to do is check your hemoglobin. Anemia can be diagnosed with routine blood test. You do not need any specialized test to diagnose anemia. Hemoglobin level is included in a simple blood test called CBC or complete blood count. A hemoglobin level of less than 13 grams per deciliter is generally considered diagnostic for anemia in men whereas a hemoglobin level of less than 12 grams per deciliter is generally considered diagnostic for anemia in women.

Although it is easy to establish the diagnosis of anemia with a simple blood test, it may take specialized tests and careful evaluation by specialists to find out the exact type and cause of anemia in any individual patient. If you are diagnosed to have anemia, you need to ask your doctor about what type of anemia you have. You also need to ask what might have caused your anemia because the treatment depends on the exact type, severity and cause of anemia.

Causes of anemia

There are many causes of anemia. There are several different types of anemia based on those causes of anemia.

Iron deficiency anemia Iron deficiency anemia is the most common type of anemia. The severity of iron deficiency anemia symptoms depends on how fast the anemia developed. There are many different causes of iron deficiency. We will look into two of these important iron deficiency causes.

Iron deficiency causes

Iron deficiency caused by bleeding

Slow bleeding over a long period of time may cause iron deficiency. Rapid bleeding may also cause iron deficiency. Iron deficiency anemia caused by bleeding is also called hemorrhagic anemia, which literally means anemia from bleeding. When people have excessive blood loss, they lose significant amount of iron that is present in the hemoglobin. This depletes the storage of iron in those people.

Iron deficiency anemia symptoms in women may be related to heavy menstrual bleeding. Anemia due to iron deficiency in men may be related to slow bleeding from their colon or other parts of the gut. Internal bleeding anemia, nose bleeds anemia, bleeding ulcers anemia and heavy menstrual bleeding anemia eventually all lead to depletion of iron store.

Iron deficiency symptoms in men require more extensive evaluation than women because men do not have any natural causes of routine blood loss.

Iron deficiency caused by nutritional problems

Iron deficiency caused by lack of iron rich foods is more common in developing countries than in the United States. However, it can still happen here in people who are on a restrictive diet. People on vegan or vegetarian diet may develop iron deficiency if they do not routinely include iron rich foods foods in their meals. Nutritional iron deficiency anemia develops slowly over a long period of time.

Iron deficiency test

Here are the 3 most common and helpful iron deficiency tests:

  1. Iron level: This iron deficiency test measures the actual amount of iron in the blood. The normal iron level for males is 55 to 160 micrograms per deciliter and that for females is 40 to 155 micrograms per deciliter.
  2. Total Iron-binding capacity: This iron deficiency test measures the capacity of the protein that carries iron in the blood. With iron deficiency this binding capacity goes up as a compensatory mechanism.
  3. Ferritin: This iron deficiency test indirectly measures your body’s iron storage. Low ferritin usually means that your iron storage is depleted.

Cancer related anemia

Cancer patients frequently develop anemia. Cancer can cause anemia in many different ways. People may develop severe nutritional deficiencies as a result of the cancer. Anemia in cancer patient may be related to this nutritional problem. Cancer can also cause bleeding and that can lead to iron deficiency anemia. Cancer or its treatment can also damage the bone marrow and it can lead to anemia. Certain cancers also induce the destruction of red blood cells and cause severe anemia.

Anemia related to kidney failure

Kidney failure is another important cause of anemia. Kidney failure leads to anemia by impairment of an important step in the production of red blood cells.

Vitamin b12 deficiency anemia

Vitamin B12 deficiency anemia may be caused by insufficient vitamin B12 in your diet or it may also be caused by problems with vitamin B12 absorption in your stomach. In addition to the common anemia symptoms described in this article, people with severe vitamin B12 deficiency anemia may have symptoms of nerve damage.

Here are some of the potential nerve damage symptoms from vitamin B12 deficiency:

  1. Memory loss
  2. Depression
  3. Problems with balance
  4. Numbness and tingling of hand and feet

Folic acid anemia

Anemia caused by deficiency of folic acid in the diet is similar to vitamin B12 deficiency anemia. Unlike B12 deficiency, folate deficiency does not usually cause nerve damage symptoms.

Sickle cell disease

Sickle cell disease is an important cause of anemia in African Americans. Sickle cell anemia results from a defective gene that makes abnormal hemoglobin in people with sickle cell disease. Anemia in sickle cell disease is accompanied by other symptoms of sickle cell disease such as extremely painful sickle cell crisis.

Hemolytic anemia (the destruction of red blood cells)

Anemia may also be caused by the destruction of red blood cells. It happens in a number of different diseases and conditions. In addition to the common symptoms of anemia described in this article, hemolytic anemia may also cause jaundice or yellow discoloration of the skin.

Severe anemia symptoms: Can you die from anemia?

It is very unusual to die from chronic anemia but severe acute anemia resulting from internal bleeding can be fatal. People with severe anemia from loss of significant amount of blood in a short period of time can die from anemia if left untreated.

Anemia treatments: How to cure anemia?

It is important to know the exact type and severity of anemia before you seek treatment. Treatment for anemia should not be attempted at home without proper diagnosis. A list of iron rich foods will not help you unless you know the exact type of anemia you have. In fact, some types of anemia will get worse by taking iron supplements. If you have severe anemia from excessive bleeding, you may need hospitalization and blood transfusion. Anemia treatment diet will only work if your anemia is related to dietary deficiency. For example, if you are found to have problems with absorption of vitamin b12, your vitamin b12 deficiency anemia will not improve by simply starting anemia treatment diet.

If you are already diagnosed with anemia, I suggest you ask your doctor what type of anemia you have before seeking any treatment.

Iron deficiency treatment

Iron deficiency treatment should only be started after confirming the diagnosis. After confirming the diagnosis of iron deficiency, you need to make sure you do not have excessive blood loss leading to the iron deficiency. In women this could be related to heavy menstrual bleeding.

In both men and women, any unexplained iron deficiency anemia warrants cancer screening and screening for possible internal bleeding. After ruling out secondary causes of Iron deficiency, you may treat iron deficiency with iron supplements and iron deficiency treatment foods.

Anemia diet for people with nutritional iron deficiency should include a combination of heme iron foods and non-heme iron foods.

Heme iron (anemia treatment foods that are easily absorbed)

  1. Beef
  2. Chicken
  3. Clams
  4. Crabs
  5. Fish
  6. Lamb
  7. Liver
  8. Oysters
  9. Pork
  10. Sardines
  11. Scallops
  12. Shrimp
  13. Tuna
  14. Turkey

Non-heme iron (anemia treatment foods that are not easily absorbed, better to combine with heme iron food for better absorption)

  1. Asparagus
  2. Baked
  3. Collard
  4. Eggs
  5. Fortified bread
  6. Iron-fortified cereal
  7. kale
  8. Lentils
  9. Mushrooms
  10. Mustard
  11. Peas
  12. Potato
  13. Pumpkin seeds
  14. Soy burger
  15. Soy milk
  16. Spears
  17. Spinach
  18. Swiss chard
  19. Tofu
  20. Tomatoes
  21. Turnip

If you already have iron deficiency anemia, anemia diet by itself is usually not enough to make anemia go away. You will need iron supplements for that. Anemia diet is more important in anemia prevention than anemia treatment.

Anemia prognosis: Can anemia go away?

Anemia is a curable condition in most people. Anemia can go away completely with treatment in most people. I am saying “most people” because certain types of anemia are difficult to treat. Anemia due to cancer may be incurable if the underlying cancer can’t be cured. Similarly anemia due to certain bone marrow problems may not be curable. Even when anemia is not curable, it is still treatable with blood transfusion.